Administration should include

Unscrew the yellow or green cap and remove the EpiPen from its storage tube.
Grasp the pen with the black tip pointing down.
Form a fist around the unit with the black tip down, and with your other hand, pull off the gray safety release.
Hold the black tip near the client's outer thigh.
Swing and jab the pen firmly into the client's outer thigh until the pen clicks so that the unit is perpendicular (i.e., a 90º angle) to the thigh.
Hold firmly against the thigh for approximately 10 seconds—injection is complete; auto-injector will show red.
Remove the unit from the thigh and massage injection area for 10 seconds.
Call 911 and seek immediate medical attention.
Carefully place the used auto-injector needle-end first into the storage tube of the carrying case that provides a built-in needle protection after use.
Screw the cap of the storage tube back on completely and take it with the client to the hospital emergency room.

Never put your thumb, fingers, or hand over the black tip.
Do not remove the gray safety release until you are ready to use the pen
Do not use if the solution is discolored or a red flag appears in the clear window.
Do not place patient insert or any other foreign objects in carriers with the auto-injector as this may prevent removing the auto-injector for use.

See VBON student handouts 4.1—4.2. Note: The auto-injector is designed to work through clothing.