Describe factors that affect dose determination.
Description should include the importance of referencing drug inserts, labeling guidelines, and other drug instructions and the ways that
- health history
- genetics
- metabolism
- age
- sex
- size
- health status
can impact dose determination.
Process/Skill Questions:
- Why might an animal such as a mouse require proportionately more of a drug than a large dog?
- Why is it important to know when the last dose of a drug would need to be administered when treating a dairy cow or pig?
- Why might two animals of the same species, breed, and weight who have undergone the same procedure require different doses of the same medication?
- What is meant by Extra Label Drug Use (ELDU) or “Off-Label Use”?